学科分类 - 《中国大百科全书》第三版网络版

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口服缓控释给药系统/ oral sustained/controlled release drug delivery systems // oral sustained/controlled release drug delivery systems /

在规定释放介质中，按要求缓慢地非恒速释放药物或接近恒速或恒速释放药物，给药频率比普通制剂有所减少，能显著增加患者用药顺应性的口服制剂。

骨架型缓控释制剂/ matrix sustained/controlled release preparations /matrix sustained/controlled release preparations
骨架型缓控释制剂
药物和一种或多种惰性固体骨架材料通过压制或融合等特定工艺制成的缓控释制剂。
膜控型缓控释制剂/ film coated sustained/controlled release preparations /film coated sustained/controlled release preparations
膜控型缓控释制剂
用一种或多种包衣材料对片剂、颗粒和微丸等进行包衣处理，通过扩散机制控制药物的释放速率、释放时间或释放部位的制剂。
渗透泵控释制剂/ osmotic pump controlled release preparations /osmotic pump controlled release preparations
渗透泵控释制剂
由药物、半透膜材料、渗透压活性物质和助推剂等组成的，以渗透压作为释药动力，以零级释放动力学为特征的一种给药系统。
单层渗透泵片/ elementary osmotic pump tablets /elementary osmotic pump tablets
单层渗透泵片
将药物与适宜的渗透活性物质制成片芯后，用醋酸纤维素等不溶性高分子材料对片芯进行包衣，形成半透性的刚性外膜，然后用激光或机械方式在该膜上开孔径适宜的释药小孔制得的控释片。
双层渗透泵片/ push-pull osmotic pump tablets /push-pull osmotic pump tablets
双层渗透泵片
以渗透压为驱动力，片芯为双层片的控释片。
多单元缓控释制剂/ multiple-unit sustained/controlled release preparations /multiple-unit sustained/controlled release preparations
多单元缓控释制剂
将缓控释颗粒、微丸或微片等填充于胶囊或压制成片剂而获得的一种缓控释制剂。
骨架型多颗粒缓释制剂/ matrix multiparticulate sustained release preparations /matrix multiparticulate sustained release preparations
骨架型多颗粒缓释制剂
将药物与适宜的骨架材料混合后，通过挤出-滚圆等工艺制备的颗粒或者小丸状制剂。
布洛芬缓释胶囊/ ibuprofen sustained release capsules /ibuprofen sustained release capsules
布洛芬缓释胶囊
内容物为白色球形小丸的缓释胶囊，为解热镇痛类非处方药。
膜控型多颗粒缓释制剂/ film coated multiparticulate sustained release preparations /film coated multiparticulate sustained release preparations
膜控型多颗粒缓释制剂
在载药丸芯外部包裹一层功能性衣膜而制成的颗粒或小丸状制剂。
地尔硫䓬缓释胶囊/ diltiazem sustained release capsules /diltiazem sustained release capsules
地尔硫䓬缓释胶囊
用于治疗各类心绞痛，轻、中度原发性高血压等。其形态为内含白色或类白色球形小丸的硬胶囊。

口服缓控释给药系统/ oral sustained/controlled release drug delivery systems // oral sustained/controlled release drug delivery systems /

骨架型缓控释制剂/ matrix sustained/controlled release preparations /matrix sustained/controlled release preparations

膜控型缓控释制剂/ film coated sustained/controlled release preparations /film coated sustained/controlled release preparations

渗透泵控释制剂/ osmotic pump controlled release preparations /osmotic pump controlled release preparations

单层渗透泵片/ elementary osmotic pump tablets /elementary osmotic pump tablets

双层渗透泵片/ push-pull osmotic pump tablets /push-pull osmotic pump tablets

多单元缓控释制剂/ multiple-unit sustained/controlled release preparations /multiple-unit sustained/controlled release preparations

骨架型多颗粒缓释制剂/ matrix multiparticulate sustained release preparations /matrix multiparticulate sustained release preparations

布洛芬缓释胶囊/ ibuprofen sustained release capsules /ibuprofen sustained release capsules

膜控型多颗粒缓释制剂/ film coated multiparticulate sustained release preparations /film coated multiparticulate sustained release preparations

地尔硫䓬缓释胶囊/ diltiazem sustained release capsules /diltiazem sustained release capsules